STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV46389.1Haloacid dehalogenase domain protein hydrolase; COGs: COG4087 Soluble P-type ATPase; InterPro IPR005834; KEGG: sun:SUN_1830 hypothetical protein; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: Putative uncharacterized protein; PFAM: haloacid dehalogenase-like hydrolase. (155 aa)    
Predicted Functional Partners:
ADV46390.1
SMC domain protein; May be involved in recombinational repair of damaged DNA.
       0.773
ADV46388.1
Enoyl-(acyl-carrier-protein) reductase (NADH); COGs: COG0623 Enoyl-(acyl-carrier-protein); InterPro IPR002198: IPR002347; KEGG: sun:SUN_0717 enoyl-(acyl carrier protein) reductase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Enoyl-[acyl-carrier protein] reductase (NADH); PFAM: short chain dehydrogenase.
       0.576
nadK
ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
       0.444
ADV46493.1
COGs: COG1237 Metal-dependent hydrolase of the beta-lactamase superfamily II; KEGG: nam:NAMH_1777 metal-dependent hydrolase of the beta-lactamase superfamily; SPTR: Metal-dependent hydrolase of the beta-lactamase superfamily; PFAM: Metallo-beta-lactamase superfamily.
  
     0.406
Your Current Organism:
Nitratifractor salsuginis
NCBI taxonomy Id: 749222
Other names: N. salsuginis DSM 16511, Nitratifractor salsuginis DSM 16511, Nitratifractor salsuginis E9I37-1, Nitratifractor salsuginis str. DSM 16511, Nitratifractor salsuginis strain DSM 16511
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