node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADV45756.1 | ADV46591.1 | Nitsa_0486 | Nitsa_1340 | UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | KEGG: sun:SUN_1127 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.766 |
ADV45756.1 | ADV46981.1 | Nitsa_0486 | Nitsa_1735 | UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | Glycosyl transferase, family 4, conserved region; COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; InterPro IPR018481: IPR018480; KEGG: sun:SUN_1556 glycosyl transferase; PFAM: Glycosyl transferase, family 4, conserved region; SPTR: Glycosyl transferase; PFAM: Glycosyl transferase family 4. | 0.765 |
ADV45756.1 | ADV47249.1 | Nitsa_0486 | Nitsa_2007 | UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.997 |
ADV45756.1 | mraY | Nitsa_0486 | Nitsa_0487 | UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.986 |
ADV45756.1 | murE | Nitsa_0486 | Nitsa_0126 | UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.992 |
ADV45756.1 | murG | Nitsa_0486 | Nitsa_1578 | UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.981 |
ADV46589.1 | ADV46591.1 | Nitsa_1338 | Nitsa_1340 | Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001867: IPR001789; KEGG: nis:NIS_1834 two-component response regulator; PFAM: transcriptional regulator domain-containing protein; SPTR: Two-component response regulator; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. | KEGG: sun:SUN_1127 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.559 |
ADV46589.1 | metG | Nitsa_1338 | Nitsa_1339 | Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001867: IPR001789; KEGG: nis:NIS_1834 two-component response regulator; PFAM: transcriptional regulator domain-containing protein; SPTR: Two-component response regulator; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.564 |
ADV46591.1 | ADV45756.1 | Nitsa_1340 | Nitsa_0486 | KEGG: sun:SUN_1127 hypothetical protein; SPTR: Putative uncharacterized protein. | UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.766 |
ADV46591.1 | ADV46589.1 | Nitsa_1340 | Nitsa_1338 | KEGG: sun:SUN_1127 hypothetical protein; SPTR: Putative uncharacterized protein. | Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001867: IPR001789; KEGG: nis:NIS_1834 two-component response regulator; PFAM: transcriptional regulator domain-containing protein; SPTR: Two-component response regulator; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. | 0.559 |
ADV46591.1 | ADV46592.1 | Nitsa_1340 | Nitsa_1341 | KEGG: sun:SUN_1127 hypothetical protein; SPTR: Putative uncharacterized protein. | dUTPase; InterPro IPR014871; KEGG: sun:SUN_1566 dUTP diphosphatase; PFAM: dUTPase; SPTR: DUTP diphosphatase; PFAM: dUTPase. | 0.474 |
ADV46591.1 | ADV46593.1 | Nitsa_1340 | Nitsa_1342 | KEGG: sun:SUN_1127 hypothetical protein; SPTR: Putative uncharacterized protein. | Asparaginase/glutaminase; COGs: COG0252 L-asparaginase/ Glu-tRNAGln amidotransferase subunit D; InterPro IPR006034; KEGG: sun:SUN_0716 asparaginase; PFAM: Asparaginase/glutaminase; SPTR: Asparaginase; PFAM: Asparaginase. | 0.474 |
ADV46591.1 | ADV46981.1 | Nitsa_1340 | Nitsa_1735 | KEGG: sun:SUN_1127 hypothetical protein; SPTR: Putative uncharacterized protein. | Glycosyl transferase, family 4, conserved region; COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; InterPro IPR018481: IPR018480; KEGG: sun:SUN_1556 glycosyl transferase; PFAM: Glycosyl transferase, family 4, conserved region; SPTR: Glycosyl transferase; PFAM: Glycosyl transferase family 4. | 0.641 |
ADV46591.1 | ADV47249.1 | Nitsa_1340 | Nitsa_2007 | KEGG: sun:SUN_1127 hypothetical protein; SPTR: Putative uncharacterized protein. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.605 |
ADV46591.1 | metG | Nitsa_1340 | Nitsa_1339 | KEGG: sun:SUN_1127 hypothetical protein; SPTR: Putative uncharacterized protein. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.804 |
ADV46591.1 | mraY | Nitsa_1340 | Nitsa_0487 | KEGG: sun:SUN_1127 hypothetical protein; SPTR: Putative uncharacterized protein. | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.656 |
ADV46591.1 | murE | Nitsa_1340 | Nitsa_0126 | KEGG: sun:SUN_1127 hypothetical protein; SPTR: Putative uncharacterized protein. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.625 |
ADV46591.1 | murG | Nitsa_1340 | Nitsa_1578 | KEGG: sun:SUN_1127 hypothetical protein; SPTR: Putative uncharacterized protein. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.693 |
ADV46592.1 | ADV46591.1 | Nitsa_1341 | Nitsa_1340 | dUTPase; InterPro IPR014871; KEGG: sun:SUN_1566 dUTP diphosphatase; PFAM: dUTPase; SPTR: DUTP diphosphatase; PFAM: dUTPase. | KEGG: sun:SUN_1127 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.474 |
ADV46592.1 | ADV46593.1 | Nitsa_1341 | Nitsa_1342 | dUTPase; InterPro IPR014871; KEGG: sun:SUN_1566 dUTP diphosphatase; PFAM: dUTPase; SPTR: DUTP diphosphatase; PFAM: dUTPase. | Asparaginase/glutaminase; COGs: COG0252 L-asparaginase/ Glu-tRNAGln amidotransferase subunit D; InterPro IPR006034; KEGG: sun:SUN_0716 asparaginase; PFAM: Asparaginase/glutaminase; SPTR: Asparaginase; PFAM: Asparaginase. | 0.807 |