node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADV45756.1 | ADV46185.1 | Nitsa_0486 | Nitsa_0925 | UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | Cell cycle protein; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182; KEGG: sun:SUN_1372 cell shape-determining protein RodA; PFAM: cell cycle protein; SPTR: Cell shape-determining protein RodA; PFAM: Cell cycle protein; TIGRFAM: rod shape-determining protein RodA; Belongs to the SEDS family. | 0.805 |
ADV45756.1 | ADV46703.1 | Nitsa_0486 | Nitsa_1454 | UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | Mur ligase middle domain protein; COGs: COG0770 UDP-N-acetylmuramyl pentapeptide synthase; InterPro IPR013221: IPR004101; KEGG: sun:SUN_0832 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate- -D-alanyl- D-alanine ligase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; SPTR:UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-al anineligase; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase middle domain. | 0.965 |
ADV45756.1 | ADV46827.1 | Nitsa_0486 | Nitsa_1579 | UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | Cell cycle protein; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182; KEGG: sun:SUN_0320 cell division protein FtsW; PFAM: cell cycle protein; SPTR: Cell division protein FtsW; PFAM: Cell cycle protein; Belongs to the SEDS family. | 0.886 |
ADV45756.1 | ADV46828.1 | Nitsa_0486 | Nitsa_1580 | UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | Peptidoglycan glycosyltransferase; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR001460; KEGG: sun:SUN_0319 cell division protein FtsI; PFAM: penicillin-binding protein transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Cell division protein FtsI; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain. | 0.860 |
ADV45756.1 | ADV47249.1 | Nitsa_0486 | Nitsa_2007 | UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.997 |
ADV45756.1 | ddl | Nitsa_0486 | Nitsa_1940 | UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | D-alanine/D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.932 |
ADV45756.1 | mraY | Nitsa_0486 | Nitsa_0487 | UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.986 |
ADV45756.1 | murA | Nitsa_0486 | Nitsa_1088 | UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.837 |
ADV45756.1 | murE | Nitsa_0486 | Nitsa_0126 | UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.992 |
ADV45756.1 | murG | Nitsa_0486 | Nitsa_1578 | UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.981 |
ADV46185.1 | ADV45756.1 | Nitsa_0925 | Nitsa_0486 | Cell cycle protein; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182; KEGG: sun:SUN_1372 cell shape-determining protein RodA; PFAM: cell cycle protein; SPTR: Cell shape-determining protein RodA; PFAM: Cell cycle protein; TIGRFAM: rod shape-determining protein RodA; Belongs to the SEDS family. | UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.805 |
ADV46185.1 | ADV46703.1 | Nitsa_0925 | Nitsa_1454 | Cell cycle protein; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182; KEGG: sun:SUN_1372 cell shape-determining protein RodA; PFAM: cell cycle protein; SPTR: Cell shape-determining protein RodA; PFAM: Cell cycle protein; TIGRFAM: rod shape-determining protein RodA; Belongs to the SEDS family. | Mur ligase middle domain protein; COGs: COG0770 UDP-N-acetylmuramyl pentapeptide synthase; InterPro IPR013221: IPR004101; KEGG: sun:SUN_0832 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate- -D-alanyl- D-alanine ligase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; SPTR:UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-al anineligase; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase middle domain. | 0.748 |
ADV46185.1 | ADV46827.1 | Nitsa_0925 | Nitsa_1579 | Cell cycle protein; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182; KEGG: sun:SUN_1372 cell shape-determining protein RodA; PFAM: cell cycle protein; SPTR: Cell shape-determining protein RodA; PFAM: Cell cycle protein; TIGRFAM: rod shape-determining protein RodA; Belongs to the SEDS family. | Cell cycle protein; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182; KEGG: sun:SUN_0320 cell division protein FtsW; PFAM: cell cycle protein; SPTR: Cell division protein FtsW; PFAM: Cell cycle protein; Belongs to the SEDS family. | 0.420 |
ADV46185.1 | ADV46828.1 | Nitsa_0925 | Nitsa_1580 | Cell cycle protein; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182; KEGG: sun:SUN_1372 cell shape-determining protein RodA; PFAM: cell cycle protein; SPTR: Cell shape-determining protein RodA; PFAM: Cell cycle protein; TIGRFAM: rod shape-determining protein RodA; Belongs to the SEDS family. | Peptidoglycan glycosyltransferase; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR001460; KEGG: sun:SUN_0319 cell division protein FtsI; PFAM: penicillin-binding protein transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Cell division protein FtsI; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain. | 0.919 |
ADV46185.1 | ADV47249.1 | Nitsa_0925 | Nitsa_2007 | Cell cycle protein; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182; KEGG: sun:SUN_1372 cell shape-determining protein RodA; PFAM: cell cycle protein; SPTR: Cell shape-determining protein RodA; PFAM: Cell cycle protein; TIGRFAM: rod shape-determining protein RodA; Belongs to the SEDS family. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.857 |
ADV46185.1 | ddl | Nitsa_0925 | Nitsa_1940 | Cell cycle protein; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182; KEGG: sun:SUN_1372 cell shape-determining protein RodA; PFAM: cell cycle protein; SPTR: Cell shape-determining protein RodA; PFAM: Cell cycle protein; TIGRFAM: rod shape-determining protein RodA; Belongs to the SEDS family. | D-alanine/D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.728 |
ADV46185.1 | mraY | Nitsa_0925 | Nitsa_0487 | Cell cycle protein; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182; KEGG: sun:SUN_1372 cell shape-determining protein RodA; PFAM: cell cycle protein; SPTR: Cell shape-determining protein RodA; PFAM: Cell cycle protein; TIGRFAM: rod shape-determining protein RodA; Belongs to the SEDS family. | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.698 |
ADV46185.1 | murA | Nitsa_0925 | Nitsa_1088 | Cell cycle protein; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182; KEGG: sun:SUN_1372 cell shape-determining protein RodA; PFAM: cell cycle protein; SPTR: Cell shape-determining protein RodA; PFAM: Cell cycle protein; TIGRFAM: rod shape-determining protein RodA; Belongs to the SEDS family. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.775 |
ADV46185.1 | murE | Nitsa_0925 | Nitsa_0126 | Cell cycle protein; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182; KEGG: sun:SUN_1372 cell shape-determining protein RodA; PFAM: cell cycle protein; SPTR: Cell shape-determining protein RodA; PFAM: Cell cycle protein; TIGRFAM: rod shape-determining protein RodA; Belongs to the SEDS family. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.737 |
ADV46185.1 | murG | Nitsa_0925 | Nitsa_1578 | Cell cycle protein; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182; KEGG: sun:SUN_1372 cell shape-determining protein RodA; PFAM: cell cycle protein; SPTR: Cell shape-determining protein RodA; PFAM: Cell cycle protein; TIGRFAM: rod shape-determining protein RodA; Belongs to the SEDS family. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.890 |