STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ADV46994.1Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002880: IPR005476; KEGG: sun:SUN_0200 pyruvate flavodoxin oxidoreductase subunit alpha; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain-containing protein; SPTR: Pyruvate:ferredoxin oxidoreductase, alpha subunit; PFAM: domain; Transketolase, C-terminal domain. (413 aa)    
Predicted Functional Partners:
ADV46993.1
Thiamine pyrophosphate TPP-binding domain-containing protein; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: sun:SUN_0201 pyruvate:ferredoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Pyruvate:ferredoxin oxidoreductase, beta subunit; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.
 0.999
ADV46996.1
Pyruvate/ketoisovalerate oxidoreductase, gamma subunit; COGs: COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase gamma subunit; InterPro IPR019752: IPR011894; KEGG: sun:SUN_0198 pyruvate flavodoxin oxidoreductase subunit gamma; PFAM: Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; SPTR: Pyruvate:ferredoxin oxidoreductase, gamma subunit; TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerat [...]
 
 0.998
ADV46995.1
COGs: COG1144 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase delta subunit; InterPro IPR017896: IPR011898: IPR017900; KEGG: sun:SUN_0199 pyruvate flavodoxin oxidoreductase subunit delta; SPTR: Pyruvate:ferredoxin oxidoreductase, delta subunit; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S binding domain; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family.
 
 0.997
ADV45642.1
2-oxoglutarate ferredoxin oxidoreductase, beta subunit; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: ant:Arnit_2141 thiamine pyrophosphate protein domain-containing protein; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; PRIAM: 2-oxoglutarate synthase; SPTR: Thiamine pyrophosphate protein domain protein TPP-binding protein; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.
  
 0.967
ADV46024.1
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
    
 0.942
ADV45845.1
ATP-citrate lyase/succinyl-CoA ligase; COGs: COG0074 Succinyl-CoA synthetase alpha subunit; InterPro IPR005810: IPR017440: IPR005811; KEGG: nis:NIS_0653 ATP citrate synthase, subunit 2; PFAM: ATP-citrate lyase/succinyl-CoA ligase; SPTR: ATP citrate synthase, subunit 2; PFAM: CoA-ligase; Citrate synthase.
  
 
 0.941
ADV46509.1
Biotin/lipoyl attachment domain-containing protein; COGs: COG5016 Pyruvate/oxaloacetate carboxyltransferase; InterPro IPR000891: IPR000089: IPR001882; KEGG: sun:SUN_1433 Na+-transporting oxaloacetate decarboxylase, alpha subunit; PFAM: biotin/lipoyl attachment domain-containing protein; pyruvate carboxyltransferase; SPTR: Na+-transporting oxaloacetate decarboxylase, alpha subunit; PFAM: HMGL-like; Biotin-requiring enzyme; Conserved carboxylase domain.
    
 0.932
ADV45345.1
COGs: COG3259 Coenzyme F420-reducing hydrogenase alpha subunit; InterPro IPR001501; KEGG: tdn:Suden_1437 nickel-dependent hydrogenase, large subunit; PFAM: nickel-dependent hydrogenase large subunit; SPTR: Nickel-dependent hydrogenase, large subunit; PFAM: Nickel-dependent hydrogenase.
   
 
 0.925
ADV45344.1
COGs: COG1740 Ni Fe-hydrogenase I small subunit; InterPro IPR001821; KEGG: tdn:Suden_1438 Ni-Fe hydrogenase, small subunit; SPTR: Ni-Fe hydrogenase, small subunit; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit.
   
 
 0.919
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.917
Your Current Organism:
Nitratifractor salsuginis
NCBI taxonomy Id: 749222
Other names: N. salsuginis DSM 16511, Nitratifractor salsuginis DSM 16511, Nitratifractor salsuginis E9I37-1, Nitratifractor salsuginis str. DSM 16511, Nitratifractor salsuginis strain DSM 16511
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