STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV47245.1COGs: COG4974 Site-specific recombinase XerD; InterPro IPR004107: IPR002104; KEGG: sun:SUN_0421 site-specific DNA tyrosine recombinase XerD; PFAM: integrase family protein; integrase domain protein SAM domain protein; SPTR: Site-specific DNA tyrosine recombinase XerD; PFAM: Phage integrase, N-terminal SAM-like domain; Phage integrase family; Belongs to the 'phage' integrase family. (276 aa)    
Predicted Functional Partners:
ADV47246.1
KEGG: sun:SUN_0420 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.788
ADV47247.1
KEGG: sun:SUN_0419 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.741
ADV46046.1
DNA translocase FtsK; COGs: COG1674 DNA segregation ATPase FtsK/SpoIIIE and related protein; InterPro IPR003593: IPR002543: IPR018541; KEGG: sun:SUN_1351 cell division protein FtsK; PFAM: cell divisionFtsK/SpoIIIE; DNA translocase ftsK gamma; SMART: AAA ATPase; SPTR: Cell division protein FtsK; PFAM: Ftsk gamma domain; FtsK/SpoIIIE family.
  
   
 0.711
mutS2
Smr protein/MutS2; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
       0.588
recR
DNA replication and repair protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
  
   
 0.574
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
  
 0.561
ADV45551.1
COGs: COG0287 Prephenate dehydrogenase; InterPro IPR003099; KEGG: sun:SUN_1998 prephenate dehydrogenase; PFAM: Prephenate dehydrogenase; SPTR: Prephenate dehydrogenase; PFAM: Prephenate dehydrogenase.
  
    0.544
ADV46768.1
COGs: COG1040 amidophosphoribosyltransferase; InterPro IPR000836; KEGG: sun:SUN_1049 transformation system protein; PFAM: phosphoribosyltransferase; SPTR: Transformation system protein; PFAM: Phosphoribosyl transferase domain.
   
    0.541
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
    0.539
ADV45711.1
parB-like partition protein; COGs: COG1475 transcriptional regulator protein; InterPro IPR004437: IPR003115; KEGG: sun:SUN_1777 chromosome partitioning protein ParB; PFAM: ParB domain protein nuclease; SMART: ParB domain protein nuclease; SPTR: Chromosome partitioning protein ParB; TIGRFAM: parB-like partition protein; PFAM: ParB-like nuclease domain; TIGRFAM: ParB-like partition proteins; Belongs to the ParB family.
  
  
 0.513
Your Current Organism:
Nitratifractor salsuginis
NCBI taxonomy Id: 749222
Other names: N. salsuginis DSM 16511, Nitratifractor salsuginis DSM 16511, Nitratifractor salsuginis E9I37-1, Nitratifractor salsuginis str. DSM 16511, Nitratifractor salsuginis strain DSM 16511
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