node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FAD_0021 | FAD_0023 | FAD_0021 | FAD_0023 | Transcriptional regulatory protein. | peptidyl-tRNA hydrolase. | 0.826 |
FAD_0021 | carS | FAD_0021 | FAD_0022 | Transcriptional regulatory protein. | Hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | 0.864 |
FAD_0023 | FAD_0021 | FAD_0023 | FAD_0021 | peptidyl-tRNA hydrolase. | Transcriptional regulatory protein. | 0.826 |
FAD_0023 | carS | FAD_0023 | FAD_0022 | peptidyl-tRNA hydrolase. | Hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | 0.937 |
FAD_0107 | FAD_1598 | FAD_0107 | FAD_1598 | Triosephosphate isomerase; Belongs to the triosephosphate isomerase family. | 50S ribosomal protein L18e. | 0.464 |
FAD_0107 | carS | FAD_0107 | FAD_0022 | Triosephosphate isomerase; Belongs to the triosephosphate isomerase family. | Hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | 0.664 |
FAD_0107 | dnaG | FAD_0107 | FAD_0128 | Triosephosphate isomerase; Belongs to the triosephosphate isomerase family. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | 0.422 |
FAD_0107 | pyrE | FAD_0107 | FAD_0079 | Triosephosphate isomerase; Belongs to the triosephosphate isomerase family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.512 |
FAD_0115 | FAD_1598 | FAD_0115 | FAD_1598 | Hypothetical protein. | 50S ribosomal protein L18e. | 0.586 |
FAD_0115 | carS | FAD_0115 | FAD_0022 | Hypothetical protein. | Hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | 0.668 |
FAD_1079 | FAD_1222 | FAD_1079 | FAD_1222 | Digeranylgeranylglycerophospholipid reductase; Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3- diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di- O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains; Belongs to the geranylgeranyl reductase family. DGGGPL reductase subfamily. | (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase. | 0.951 |
FAD_1079 | carS | FAD_1079 | FAD_0022 | Digeranylgeranylglycerophospholipid reductase; Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3- diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di- O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains; Belongs to the geranylgeranyl reductase family. DGGGPL reductase subfamily. | Hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | 0.901 |
FAD_1222 | FAD_1079 | FAD_1222 | FAD_1079 | (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase. | Digeranylgeranylglycerophospholipid reductase; Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3- diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di- O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains; Belongs to the geranylgeranyl reductase family. DGGGPL reductase subfamily. | 0.951 |
FAD_1222 | carS | FAD_1222 | FAD_0022 | (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase. | Hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | 0.960 |
FAD_1598 | FAD_0107 | FAD_1598 | FAD_0107 | 50S ribosomal protein L18e. | Triosephosphate isomerase; Belongs to the triosephosphate isomerase family. | 0.464 |
FAD_1598 | FAD_0115 | FAD_1598 | FAD_0115 | 50S ribosomal protein L18e. | Hypothetical protein. | 0.586 |
FAD_1598 | carS | FAD_1598 | FAD_0022 | 50S ribosomal protein L18e. | Hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | 0.653 |
FAD_1598 | dnaG | FAD_1598 | FAD_0128 | 50S ribosomal protein L18e. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | 0.702 |
carS | FAD_0021 | FAD_0022 | FAD_0021 | Hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | Transcriptional regulatory protein. | 0.864 |
carS | FAD_0023 | FAD_0022 | FAD_0023 | Hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | peptidyl-tRNA hydrolase. | 0.937 |