STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAD_0122SoxB-like sarcosine oxidase, beta subunit related protein. (402 aa)    
Predicted Functional Partners:
FAD_1832
Aminomethyltransferase.
 
 
 0.972
FAD_0643
Serine hydroxymethyltransferase.
  
 
 0.916
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.916
FAD_0451
Glycine dehydrogenase subunit 2.
   
 
 0.914
FAD_0450
Glycine dehydrogenase subunit 1.
   
 
 0.907
thiI
Thiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
     
 0.778
FAD_1579
Hypothetical protein.
 
  
 0.617
FAD_0342
Sulfide dehydrogenase (flavocytochrome C).
  
 
 0.595
FAD_1225
NADH dehydrogenase.
  
 
 0.595
FAD_1731
NAD(FAD)-dependent dehydrogenase.
  
 
 0.595
Your Current Organism:
Ferroplasma acidiphilum
NCBI taxonomy Id: 74969
Other names: DSM 12658, F. acidiphilum, Ferromonas metallovorans, Ferroplasma acidiphilum Golyshina et al. 2000, JCM 10970
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.