| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FAD_0134 | FAD_0137 | FAD_0134 | FAD_0137 | O-sialoglycoprotein endopeptidase/protein kinase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | Translation initiation factor IF-2 subunit gamma. | 0.999 |
| FAD_0134 | FAD_1656 | FAD_0134 | FAD_1656 | O-sialoglycoprotein endopeptidase/protein kinase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | Translation initiation factor IF-2 subunit alpha. | 0.829 |
| FAD_0134 | rps15 | FAD_0134 | FAD_0245 | O-sialoglycoprotein endopeptidase/protein kinase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | 30S ribosomal protein S15P. | 0.999 |
| FAD_0134 | rps3 | FAD_0134 | FAD_0164 | O-sialoglycoprotein endopeptidase/protein kinase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | 30S ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. | 0.461 |
| FAD_0134 | rps5 | FAD_0134 | FAD_0179 | O-sialoglycoprotein endopeptidase/protein kinase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | 30S ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy. | 0.579 |
| FAD_0134 | rps6e | FAD_0134 | FAD_0136 | O-sialoglycoprotein endopeptidase/protein kinase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | 30S ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family. | 0.981 |
| FAD_0137 | FAD_0134 | FAD_0137 | FAD_0134 | Translation initiation factor IF-2 subunit gamma. | O-sialoglycoprotein endopeptidase/protein kinase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | 0.999 |
| FAD_0137 | FAD_1656 | FAD_0137 | FAD_1656 | Translation initiation factor IF-2 subunit gamma. | Translation initiation factor IF-2 subunit alpha. | 0.999 |
| FAD_0137 | eif1a | FAD_0137 | FAD_0202 | Translation initiation factor IF-2 subunit gamma. | Translation initiation factor IF-1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. | 0.963 |
| FAD_0137 | eif2b | FAD_0137 | FAD_1181 | Translation initiation factor IF-2 subunit gamma. | Translation initiation factor IF-2 subunit beta; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family. | 0.999 |
| FAD_0137 | rpl7ae | FAD_0137 | FAD_0589 | Translation initiation factor IF-2 subunit gamma. | Multifunctional RNA-binding protein L7Ae; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. | 0.964 |
| FAD_0137 | rps15 | FAD_0137 | FAD_0245 | Translation initiation factor IF-2 subunit gamma. | 30S ribosomal protein S15P. | 0.952 |
| FAD_0137 | rps3 | FAD_0137 | FAD_0164 | Translation initiation factor IF-2 subunit gamma. | 30S ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. | 0.955 |
| FAD_0137 | rps4e | FAD_0137 | FAD_0171 | Translation initiation factor IF-2 subunit gamma. | 30S ribosomal protein S4e; Belongs to the eukaryotic ribosomal protein eS4 family. | 0.960 |
| FAD_0137 | rps5 | FAD_0137 | FAD_0179 | Translation initiation factor IF-2 subunit gamma. | 30S ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy. | 0.961 |
| FAD_0137 | rps6e | FAD_0137 | FAD_0136 | Translation initiation factor IF-2 subunit gamma. | 30S ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family. | 0.997 |
| FAD_1656 | FAD_0134 | FAD_1656 | FAD_0134 | Translation initiation factor IF-2 subunit alpha. | O-sialoglycoprotein endopeptidase/protein kinase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | 0.829 |
| FAD_1656 | FAD_0137 | FAD_1656 | FAD_0137 | Translation initiation factor IF-2 subunit alpha. | Translation initiation factor IF-2 subunit gamma. | 0.999 |
| FAD_1656 | eif1a | FAD_1656 | FAD_0202 | Translation initiation factor IF-2 subunit alpha. | Translation initiation factor IF-1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. | 0.999 |
| FAD_1656 | eif2b | FAD_1656 | FAD_1181 | Translation initiation factor IF-2 subunit alpha. | Translation initiation factor IF-2 subunit beta; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family. | 0.999 |