Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
FAD_0434Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (416 aa)    
Predicted Functional Partners:
FAD_1098
Aspartate aminotransferase.
  
 
 0.977
FAD_1100
Citrate synthase.
   
 0.957
FAD_1632
Isocitrate dehydrogenase.
   
 0.957
FAD_0718
Malate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 
 0.948
FAD_1043
Glutamine synthetase.
  
 
 0.948
FAD_1847
Glutamine synthetase.
  
 
 0.948
FAD_0763
Carbon-nitrogen hydrolase.
  
 
 0.939
pckG
Phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
  
 
 0.937
FAD_0712
2-oxoglutarate synthase, alpha chain.
  
 
 0.931
FAD_0567
2-oxoacid--ferredoxin oxidoreductase, alpha subunit.
  
 
 0.928
Your Current Organism:
Ferroplasma acidiphilum
NCBI taxonomy Id: 74969
Other names: DSM 12658, F. acidiphilum, Ferromonas metallovorans, Ferroplasma acidiphilum Golyshina et al. 2000, JCM 10970
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