| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FAD_0134 | FAD_0158 | FAD_0134 | FAD_0158 | O-sialoglycoprotein endopeptidase/protein kinase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | 50S ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.461 |
| FAD_0134 | FAD_0161 | FAD_0134 | FAD_0161 | O-sialoglycoprotein endopeptidase/protein kinase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | 50S ribosomal protein L2P. | 0.641 |
| FAD_0134 | rps19e | FAD_0134 | FAD_0074 | O-sialoglycoprotein endopeptidase/protein kinase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | 30S ribosomal protein S19e; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. | 0.551 |
| FAD_0134 | rps24e | FAD_0134 | FAD_0458 | O-sialoglycoprotein endopeptidase/protein kinase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | 30S ribosomal protein S24e; Belongs to the eukaryotic ribosomal protein eS24 family. | 0.999 |
| FAD_0134 | rps6e | FAD_0134 | FAD_0136 | O-sialoglycoprotein endopeptidase/protein kinase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | 30S ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family. | 0.981 |
| FAD_0158 | FAD_0134 | FAD_0158 | FAD_0134 | 50S ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | O-sialoglycoprotein endopeptidase/protein kinase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | 0.461 |
| FAD_0158 | FAD_0161 | FAD_0158 | FAD_0161 | 50S ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 50S ribosomal protein L2P. | 0.999 |
| FAD_0158 | rpl21e | FAD_0158 | FAD_0045 | 50S ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 50S ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family. | 0.999 |
| FAD_0158 | rpl23 | FAD_0158 | FAD_0160 | 50S ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 50S ribosomal protein L23P; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. | 0.999 |
| FAD_0158 | rpl31e | FAD_0158 | FAD_0077 | 50S ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 50S ribosomal protein L31e; Belongs to the ribosomal protein L31e family. | 0.999 |
| FAD_0158 | rpl37ae | FAD_0158 | FAD_0042 | 50S ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 50S ribosomal protein L37Ae; Binds to the 23S rRNA. | 0.999 |
| FAD_0158 | rps19e | FAD_0158 | FAD_0074 | 50S ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 30S ribosomal protein S19e; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. | 0.999 |
| FAD_0158 | rps19p | FAD_0158 | FAD_0162 | 50S ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 30S ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. | 0.999 |
| FAD_0158 | rps24e | FAD_0158 | FAD_0458 | 50S ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 30S ribosomal protein S24e; Belongs to the eukaryotic ribosomal protein eS24 family. | 0.999 |
| FAD_0158 | rps6e | FAD_0158 | FAD_0136 | 50S ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 30S ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family. | 0.999 |
| FAD_0161 | FAD_0134 | FAD_0161 | FAD_0134 | 50S ribosomal protein L2P. | O-sialoglycoprotein endopeptidase/protein kinase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | 0.641 |
| FAD_0161 | FAD_0158 | FAD_0161 | FAD_0158 | 50S ribosomal protein L2P. | 50S ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.999 |
| FAD_0161 | rpl21e | FAD_0161 | FAD_0045 | 50S ribosomal protein L2P. | 50S ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family. | 0.999 |
| FAD_0161 | rpl23 | FAD_0161 | FAD_0160 | 50S ribosomal protein L2P. | 50S ribosomal protein L23P; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. | 0.999 |
| FAD_0161 | rpl31e | FAD_0161 | FAD_0077 | 50S ribosomal protein L2P. | 50S ribosomal protein L31e; Belongs to the ribosomal protein L31e family. | 0.999 |