Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
FAD_0468Allantoin permease family protein. (449 aa)    
Predicted Functional Partners:
FAD_0469
Deoxycytidine triphosphate deaminase.
 
     0.807
FAD_0599
Phosphomethylpyrimidine kinase.
  
  
 0.780
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
  
 0.739
FAD_0466
Phosphoribosylamine--glycine ligase.
  
    0.559
FAD_0470
Nicotinamide-nucleotide adenylyltransferase.
       0.539
FAD_0467
Thiosulfate sulfurtransferase.
       0.526
FAD_0685
Purine-cytosine permease related protein.
  
     0.525
FAD_0822
Major facilitator superfamily permease.
  
    0.507
pyrB
Aspartate carbamoyltransferase catalytic subunit.
   
    0.495
pyrI
Aspartate carbamoyltransferase regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase.
   
    0.492
Your Current Organism:
Ferroplasma acidiphilum
NCBI taxonomy Id: 74969
Other names: DSM 12658, F. acidiphilum, Ferromonas metallovorans, Ferroplasma acidiphilum Golyshina et al. 2000, JCM 10970
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