Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
FAD_0584Formate hydrogenlyase, subunit 4. (313 aa)    
Predicted Functional Partners:
FAD_0580
Ni,Fe-hydrogenase III small subunit.
 
 
 0.999
FAD_0581
Ni,Fe-hydrogenase III large subunit.
 
 
 0.997
FAD_0582
Hydrogenase 4 subunit F.
 
 
 0.994
FAD_0579
Hydrogenase 4 subunit B.
 
 
 0.989
FAD_0583
Hypothetical protein.
 
  
 0.980
FAD_0623
NADH dehydrogenase subunit I.
  
 
 0.962
FAD_0620
NADH dehydrogenase subunit C.
  
 
 0.807
FAD_0619
NADH dehydrogenase subunit B; Belongs to the complex I 20 kDa subunit family.
   
   0.746
FAD_0621
NADH dehydrogenase subunit D.
   
   0.746
FAD_0627
NADH-quinone oxidoreductase chain L.
     
 0.552
Your Current Organism:
Ferroplasma acidiphilum
NCBI taxonomy Id: 74969
Other names: DSM 12658, F. acidiphilum, Ferromonas metallovorans, Ferroplasma acidiphilum Golyshina et al. 2000, JCM 10970
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