| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FAD_0210 | deoD | FAD_0210 | FAD_0727 | Translation initiation factor IF-2B subunit alpha; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. | Purine nucleoside phosphorylase. | 0.908 |
| FAD_0210 | mtnP | FAD_0210 | FAD_1363 | Translation initiation factor IF-2B subunit alpha; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. | 5'-methylthioadenosine phosphorylase II; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.961 |
| FAD_0223 | deoD | FAD_0223 | FAD_0727 | Metal-dependent hydrolase. | Purine nucleoside phosphorylase. | 0.905 |
| FAD_0223 | mtnP | FAD_0223 | FAD_1363 | Metal-dependent hydrolase. | 5'-methylthioadenosine phosphorylase II; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.969 |
| FAD_0223 | speE | FAD_0223 | FAD_0132 | Metal-dependent hydrolase. | Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine; Belongs to the spermidine/spermine synthase family. | 0.914 |
| FAD_0353 | deoD | FAD_0353 | FAD_0727 | 6-phosphofructokinase. | Purine nucleoside phosphorylase. | 0.408 |
| FAD_0353 | rbsK | FAD_0353 | FAD_1861 | 6-phosphofructokinase. | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.587 |
| FAD_0726 | deoD | FAD_0726 | FAD_0727 | XshC/Cox1-family protein. | Purine nucleoside phosphorylase. | 0.484 |
| FAD_0728 | deoD | FAD_0728 | FAD_0727 | Transposase IS4 family protein. | Purine nucleoside phosphorylase. | 0.506 |
| deoD | FAD_0210 | FAD_0727 | FAD_0210 | Purine nucleoside phosphorylase. | Translation initiation factor IF-2B subunit alpha; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. | 0.908 |
| deoD | FAD_0223 | FAD_0727 | FAD_0223 | Purine nucleoside phosphorylase. | Metal-dependent hydrolase. | 0.905 |
| deoD | FAD_0353 | FAD_0727 | FAD_0353 | Purine nucleoside phosphorylase. | 6-phosphofructokinase. | 0.408 |
| deoD | FAD_0726 | FAD_0727 | FAD_0726 | Purine nucleoside phosphorylase. | XshC/Cox1-family protein. | 0.484 |
| deoD | FAD_0728 | FAD_0727 | FAD_0728 | Purine nucleoside phosphorylase. | Transposase IS4 family protein. | 0.506 |
| deoD | mtnP | FAD_0727 | FAD_1363 | Purine nucleoside phosphorylase. | 5'-methylthioadenosine phosphorylase II; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.921 |
| deoD | rbsK | FAD_0727 | FAD_1861 | Purine nucleoside phosphorylase. | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.408 |
| deoD | speE | FAD_0727 | FAD_0132 | Purine nucleoside phosphorylase. | Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine; Belongs to the spermidine/spermine synthase family. | 0.900 |
| mtnP | FAD_0210 | FAD_1363 | FAD_0210 | 5'-methylthioadenosine phosphorylase II; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | Translation initiation factor IF-2B subunit alpha; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. | 0.961 |
| mtnP | FAD_0223 | FAD_1363 | FAD_0223 | 5'-methylthioadenosine phosphorylase II; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | Metal-dependent hydrolase. | 0.969 |
| mtnP | deoD | FAD_1363 | FAD_0727 | 5'-methylthioadenosine phosphorylase II; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | Purine nucleoside phosphorylase. | 0.921 |