Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
gdhGlucose-1-dehydrogenase; Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD(+) and NADP(+) as electron acceptor. Is involved in the degradation of glucose through a non-phosphorylative variant of the Entner-Doudoroff pathway. (358 aa)    
Predicted Functional Partners:
FAD_1577
Hypothetical protein.
 
 
 0.925
FAD_0738
Aldose 1-epimerase.
 
 
 0.923
FAD_0324
Beta-glucosidase; Belongs to the glycosyl hydrolase 1 family.
 
  
 0.916
FAD_1215
Glucose-1-dehydrogenase.
  
  
 
0.912
FAD_0737
Glucose 1-dehydrogenase.
  
 
 0.906
gap
Glyceraldehyde-3-phosphate dehydrogenase.
  
 
 0.864
FAD_0562
Bifunctional phosphoglucose/phosphomannose isomerase.
  
 0.847
FAD_0277
ROK family glucokinase.
  
 
 0.833
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 
 0.833
FAD_1756
Pyruvate dehydrogenase E1 component alpha subunit.
  
 
 0.833
Your Current Organism:
Ferroplasma acidiphilum
NCBI taxonomy Id: 74969
Other names: DSM 12658, F. acidiphilum, Ferromonas metallovorans, Ferroplasma acidiphilum Golyshina et al. 2000, JCM 10970
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