Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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surEAcid phosphatase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (269 aa)    
Predicted Functional Partners:
FAD_1802
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
 
  
 0.943
FAD_1773
GMP synthase subunit B.
    
 0.941
FAD_1438
Adenylosuccinate lyase.
    
 0.936
tmk
Thymidylate kinase.
    
 0.933
guaAA
GMP synthase subunit A; Catalyzes the synthesis of GMP from XMP.
    
 0.929
guaB
Inosine 5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.928
FAD_0080
Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family.
    
 0.925
FAD_1332
Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase.
     
 0.922
tdk
Thymidine kinase related protein.
  
  
  0.917
FAD_0185
Cytidylate kinase.
  
  
  0.913
Your Current Organism:
Ferroplasma acidiphilum
NCBI taxonomy Id: 74969
Other names: DSM 12658, F. acidiphilum, Ferromonas metallovorans, Ferroplasma acidiphilum Golyshina et al. 2000, JCM 10970
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