STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cbiDCobalamin biosynthetic protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (354 aa)    
Predicted Functional Partners:
FAD_0338
Precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit.
  
 0.999
FAD_0798
Cobalamin biosynthesis protein CbiG.
 
 
 0.998
FAD_1282
Precorrin-6x reductase.
 
 
 0.998
FAD_1283
precorrin-8X methylmutase.
  
 0.997
cobQ
Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
  
  
 0.925
FAD_0337
Precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family.
 
  
 0.921
FAD_1120
cobalt-precorrin-3B C(17)-methyltransferase.
 
  
 0.915
FAD_0335
Precorrin-4 C11-methyltransferase.
 
  
 0.903
cobD
Cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
  
  
 0.798
cbiA
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
  
  
 0.768
Your Current Organism:
Ferroplasma acidiphilum
NCBI taxonomy Id: 74969
Other names: DSM 12658, F. acidiphilum, Ferromonas metallovorans, Ferroplasma acidiphilum Golyshina et al. 2000, JCM 10970
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