STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAD_1331Hypothetical protein. (289 aa)    
Predicted Functional Partners:
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
     0.945
FAD_0096
Helix-turn-helix domain protein.
  
     0.673
FAD_0086
Phosphoserine phosphatase.
  
     0.660
FAD_0267
Mov34/MPN/PAD-1 family protein.
  
     0.628
FAD_1775
tRNA splicing endonuclease.
  
     0.601
FAD_0565
Archaeal S2P/M50/PDZ group multipass membrane metalloprotease.
  
     0.598
FAD_0351
ATP-dependent protease Lon; Belongs to the peptidase S16 family.
  
     0.593
FAD_0259
Hypothetical protein.
  
     0.585
FAD_1623
Hypothetical protein.
  
     0.584
FAD_0453
Hypothetical protein.
  
     0.555
Your Current Organism:
Ferroplasma acidiphilum
NCBI taxonomy Id: 74969
Other names: DSM 12658, F. acidiphilum, Ferromonas metallovorans, Ferroplasma acidiphilum Golyshina et al. 2000, JCM 10970
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.