STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAD_1443Universal stress protein. (145 aa)    
Predicted Functional Partners:
FAD_0516
Potassium-transporting ATPase subunit C.
     
 0.782
FAD_0644
Inosine-5'-monophosphate dehydrogenase.
 
    0.716
rps17e
30S ribosomal protein S17e; Belongs to the eukaryotic ribosomal protein eS17 family.
       0.572
FAD_0788
CBS domain-containing protein.
 
    0.540
gap
Glyceraldehyde-3-phosphate dehydrogenase.
  
  
 0.508
guaB
Inosine 5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
      
 0.500
FAD_0403
O6-methylguanine-DNA methyltransferase/endonuclease V.
  
    0.464
FAD_1274
Dehydrogenase.
      
 0.463
ogt
methylated-DNA-[protein]-cysteine S-methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
  
    0.458
arsB
Arsenite efflux pump permease.
     
 0.458
Your Current Organism:
Ferroplasma acidiphilum
NCBI taxonomy Id: 74969
Other names: DSM 12658, F. acidiphilum, Ferromonas metallovorans, Ferroplasma acidiphilum Golyshina et al. 2000, JCM 10970
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.