STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAD_1526Thy1 protein; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (531 aa)    
Predicted Functional Partners:
FAD_0403
O6-methylguanine-DNA methyltransferase/endonuclease V.
       0.712
FAD_1525
Thermosome subunit; Belongs to the TCP-1 chaperonin family.
   
   0.626
FAD_1523
Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
       0.585
FAD_1527
NADH-dependent oxidoreductase.
     
 0.584
FAD_0469
Deoxycytidine triphosphate deaminase.
     
 0.535
pyrG
CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
     
 0.529
tmk
Thymidylate kinase.
     
 0.526
FAD_1562
Methyltransferase.
  
   0.490
FAD_0248
Type I restriction-modification system methylation subunit.
   
   0.473
FAD_1524
FAD-dependent pyridine nucleotide-disulfide oxidoreductase.
     
 0.468
Your Current Organism:
Ferroplasma acidiphilum
NCBI taxonomy Id: 74969
Other names: DSM 12658, F. acidiphilum, Ferromonas metallovorans, Ferroplasma acidiphilum Golyshina et al. 2000, JCM 10970
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.