Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
psmAProteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (234 aa)    
Predicted Functional Partners:
psmB
Proteasome beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
 
 
0.961
rpl37ae
50S ribosomal protein L37Ae; Binds to the 23S rRNA.
 
  
 0.940
FAD_0480
50S ribosomal protein L15e.
  
 0.908
FAD_0810
Glycerol kinase.
   
 0.888
FAD_0267
Mov34/MPN/PAD-1 family protein.
   
 0.876
pfdB
Prefoldin subunit beta; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
  
 
 0.874
rrp4
Exosome complex RNA-binding protein Rrp4; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome.
     
 0.853
rrp42
Exosome complex RNA-binding protein Rrp42; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site.
 
  
 0.846
FAD_0038
Putative RNA-associated protein.
 
  
 0.828
FAD_0043
DNA-directed RNA polymerase subunit P.
  
  
 0.783
Your Current Organism:
Ferroplasma acidiphilum
NCBI taxonomy Id: 74969
Other names: DSM 12658, F. acidiphilum, Ferromonas metallovorans, Ferroplasma acidiphilum Golyshina et al. 2000, JCM 10970
Server load: low (40%) [HD]