STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAD_15892-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (345 aa)    
Predicted Functional Partners:
lysU
Homoaconitase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily.
 
 
 0.969
ilvD
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
 
 0.966
lysT
Homoaconitase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 
 
 0.966
FAD_1789
3-isopropylmalate dehydratase large subunit.
 
 
 0.964
FAD_1790
3-isopropylmalate dehydratase small subunit.
  
 
 0.960
FAD_0051
acetyl-CoA acetyltransferase.
  
 
 0.921
FAD_1242
acetyl-CoA acetyltransferase.
  
 
 0.921
FAD_1550
acetyl-CoA acetyltransferase.
  
 
 0.921
hcs
Homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
  
 
0.920
FAD_1022
Acetyl-coenzyme A synthetase.
  
 
 0.916
Your Current Organism:
Ferroplasma acidiphilum
NCBI taxonomy Id: 74969
Other names: DSM 12658, F. acidiphilum, Ferromonas metallovorans, Ferroplasma acidiphilum Golyshina et al. 2000, JCM 10970
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