STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (309 aa)    
Predicted Functional Partners:
FAD_0378
Homoserine dehydrogenase.
 
 0.999
FAD_0783
Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
  
 
 0.992
FAD_1809
Hypothetical protein.
  
 
 0.988
FAD_1643
Threonine synthase.
 
 
 0.979
FAD_1716
Threonine synthase.
  
 
 0.977
FAD_1132
Aspartokinase (akH).
 
 
 0.922
FAD_0273
Methionine synthase.
 
 
 0.865
FAD_0279
Cystathionine gamma-lyase.
  
 
 0.851
FAD_1133
Aspartate-semialdehyde dehydrogenase.
 
  
 0.837
FAD_0274
Hypothetical protein.
  
 
 0.836
Your Current Organism:
Ferroplasma acidiphilum
NCBI taxonomy Id: 74969
Other names: DSM 12658, F. acidiphilum, Ferromonas metallovorans, Ferroplasma acidiphilum Golyshina et al. 2000, JCM 10970
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