node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALP61722.1 | ALP61972.1 | AN416_03305 | AN416_04730 | Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the malic enzymes family. | Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.943 |
ALP61722.1 | ALP63238.1 | AN416_03305 | AN416_11990 | Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the malic enzymes family. | Isocitrate lyase; Catalyzes the reversible formation of glyoxylate and succinate from isocitrate; glyoxylate bypass pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.719 |
ALP61722.1 | ALP63240.1 | AN416_03305 | AN416_12010 | Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the malic enzymes family. | Malate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the malate synthase family. | 0.975 |
ALP61722.1 | ALP63799.1 | AN416_03305 | AN416_15205 | Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the malic enzymes family. | Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.920 |
ALP61722.1 | ALP65987.1 | AN416_03305 | AN416_26140 | Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the malic enzymes family. | Isocitrate lyase; Catalyzes the first step in the glyoxalate cycle, which converts lipids to carbohydrates; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.719 |
ALP61722.1 | gltA-2 | AN416_03305 | AN416_27140 | Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the malic enzymes family. | Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. | 0.920 |
ALP61972.1 | ALP61722.1 | AN416_04730 | AN416_03305 | Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the malic enzymes family. | 0.943 |
ALP61972.1 | ALP63238.1 | AN416_04730 | AN416_11990 | Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Isocitrate lyase; Catalyzes the reversible formation of glyoxylate and succinate from isocitrate; glyoxylate bypass pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.719 |
ALP61972.1 | ALP63240.1 | AN416_04730 | AN416_12010 | Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Malate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the malate synthase family. | 0.975 |
ALP61972.1 | ALP63799.1 | AN416_04730 | AN416_15205 | Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.920 |
ALP61972.1 | ALP65987.1 | AN416_04730 | AN416_26140 | Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Isocitrate lyase; Catalyzes the first step in the glyoxalate cycle, which converts lipids to carbohydrates; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.719 |
ALP61972.1 | gltA-2 | AN416_04730 | AN416_27140 | Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. | 0.920 |
ALP62587.1 | ALP63240.1 | AN416_08225 | AN416_12010 | AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Malate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the malate synthase family. | 0.941 |
ALP62587.1 | ALP63799.1 | AN416_08225 | AN416_15205 | AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.939 |
ALP62587.1 | ALP66535.1 | AN416_08225 | AN416_18520 | AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.920 |
ALP62587.1 | ALP66557.1 | AN416_08225 | AN416_19285 | AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the formation of acetyl phosphate from acetyl-CoA and phosphate; can also act with other short-chain acyl-CoAs; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.911 |
ALP62587.1 | acsA | AN416_08225 | AN416_08150 | AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.917 |
ALP62587.1 | gltA-2 | AN416_08225 | AN416_27140 | AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. | 0.939 |
ALP63238.1 | ALP61722.1 | AN416_11990 | AN416_03305 | Isocitrate lyase; Catalyzes the reversible formation of glyoxylate and succinate from isocitrate; glyoxylate bypass pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. | Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the malic enzymes family. | 0.719 |
ALP63238.1 | ALP61972.1 | AN416_11990 | AN416_04730 | Isocitrate lyase; Catalyzes the reversible formation of glyoxylate and succinate from isocitrate; glyoxylate bypass pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. | Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.719 |