Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AFV75863.1Fe2+/Zn2+ uptake regulation protein; PFAM: Ferric uptake regulator family; Belongs to the Fur family. (122 aa)    
Predicted Functional Partners:
AFV76917.1
Fe2+/Zn2+ uptake regulation protein; PFAM: Ferric uptake regulator family; Belongs to the Fur family.
  
     0.723
AFV75864.1
PFAM: YibE/F-like protein.
       0.574
AFV75966.1
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
  
 0.547
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.538
AFV76148.1
PFAM: Sugar-specific transcriptional regulator TrmB.
  
    0.512
sbcD
Exonuclease SbcD; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
       0.495
AFV75866.1
ATPase involved in DNA repair; PFAM: RecF/RecN/SMC N terminal domain; TIGRFAM: exonuclease SbcC.
       0.493
AFV76935.1
Putative CoA-binding protein.
  
    0.479
AFV75868.1
PFAM: MviN-like protein; TIGRFAM: integral membrane protein MviN.
       0.473
AFV76700.1
PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
     
 0.461
Your Current Organism:
Thermus oshimai
NCBI taxonomy Id: 751945
Other names: T. oshimai JL-2, Thermus oshimai JL-2, Thermus oshimai str. JL-2, Thermus oshimai strain JL-2
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