Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AFV76934.1A/G-specific DNA glycosylase; Adenine glycosylase active on G-A mispairs. (323 aa)    
Predicted Functional Partners:
AFV75155.1
DNA-binding protein, stimulates sugar fermentation; PFAM: Sugar fermentation stimulation protein; TIGRFAM: sugar fermentation stimulation protein; Belongs to the SfsA family.
 
    0.928
AFV76942.1
PFAM: RimK-like ATP-grasp domain; TIGRFAM: Lysine biosynthesis enzyme LysX; alpha-L-glutamate ligases, RimK family; Belongs to the RimK family.
 
   
 0.833
AFV76935.1
Putative CoA-binding protein.
       0.803
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.
       0.791
lysZ
Acetylglutamate kinase; Catalyzes the phosphorylation of LysW-gamma-alpha- aminoadipate; Belongs to the acetylglutamate kinase family. LysZ subfamily.
     
 0.786
AFV76936.1
Nuclease-like protein; PFAM: Nuclease-related domain.
       0.781
AFV76938.1
Putative amidohydrolase; PFAM: Carbon-nitrogen hydrolase.
       0.780
AFV76939.1
Hypothetical protein; PFAM: Domain of unknown function (DUF1957); Glycosyl hydrolase family 57; Belongs to the glycosyl hydrolase 57 family.
       0.773
lysY
N-acetyl-gamma-glutamyl-phosphate reductase, common form; Catalyzes the NADPH-dependent reduction of [LysW]- aminoadipate 6-phosphate to yield [LysW]-aminoadipate 6-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.
       0.773
AFV76943.1
PFAM: TFIIB zinc-binding; TIGRFAM: lysine biosynthesis protein LysW.
       0.773
Your Current Organism:
Thermus oshimai
NCBI taxonomy Id: 751945
Other names: T. oshimai JL-2, Thermus oshimai JL-2, Thermus oshimai str. JL-2, Thermus oshimai strain JL-2
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