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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AQA11149.1Signal peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (94 aa)    
Predicted Functional Partners:
AQA11150.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.756
AQA11151.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.673
AQA13502.1
DUF397 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.641
AQA14923.1
DUF397 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.630
AQA14924.1
DUF397 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.604
egtD
L-histidine N(alpha)-methyltransferase; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family.
   
    0.599
AQA11790.1
DUF1508 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.579
AQA11333.1
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.556
AQA13675.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.540
AQA13712.1
DUF397 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.532
Your Current Organism:
Streptomyces autolyticus
NCBI taxonomy Id: 75293
Other names: S. autolyticus
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