STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AQA11378.1DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (121 aa)    
Predicted Functional Partners:
AQA11379.1
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.770
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
       0.732
tatA-2
Sec-independent protein translocase TatA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
  
     0.721
AQA15153.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.655
AQA11376.1
Methylenetetrahydrofolate reductase [NAD(P)H]; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family.
       0.651
AQA11375.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.634
cobB
NAD-dependent protein deacetylase 1; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class II subfamily.
   
    0.587
AQA14722.1
NAD-dependent deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.587
AQA16178.1
Glycine oxidase ThiO; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.550
AQA11380.1
Thiamine biosynthesis protein ThiS; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.550
Your Current Organism:
Streptomyces autolyticus
NCBI taxonomy Id: 75293
Other names: S. autolyticus
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