Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Rnf20E3 ubiquitin-protein ligase BRE1A isoform X1. (976 aa)    
Predicted Functional Partners:
ENSSGRP00000041033
LEO1 homolog, Paf1/RNA polymerase II complex component.
   
 0.906
leo1
RNA polymerase-associated protein LEO1.
   
 0.906
ENSSGRP00000096558
Parafibromin-like.
   
 0.896
LOC107593758
Parafibromin.
   
 0.896
ENSSGRP00000000939
PAF1 homolog, Paf1/RNA polymerase II complex component.
    
 0.883
ENSSGRP00000032271
PAF1 homolog, Paf1/RNA polymerase II complex component.
    
 0.883
ENSSGRP00000002438
WW domain-containing adapter protein with coiled-coil-like isoform X1.
   
 0.870
ENSSGRP00000004151
annotation not available
   
 0.870
wac
WW domain-containing adapter protein with coiled-coil isoform X1.
   
 0.870
ENSSGRP00000081230
WW domain-containing adapter protein with coiled-coil-like.
   
 0.870
Your Current Organism:
Sinocyclocheilus grahami
NCBI taxonomy Id: 75366
Other names: S. grahami
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.