Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSSGRP00000001781Polycomb group RING finger protein 5-A-like isoform X1. (236 aa)    
Predicted Functional Partners:
LOC107564705
E3 ubiquitin-protein ligase RING2 isoform X1.
    
 0.977
LOC107589914
E3 ubiquitin-protein ligase RING2-like.
    
 0.977
RING1
E3 ubiquitin-protein ligase RING2-A-like.
    
 0.968
auts2
Autism susceptibility gene 2 protein isoform X1.
    
 0.940
ENSSGRP00000008328
annotation not available
    
 0.940
LOC107586267
Autism susceptibility gene 2 protein-like isoform X1.
    
 0.940
ENSSGRP00000074892
Activator of transcription and developmental regulator AUTS2 a.
    
 0.940
LOC107597539
Autism susceptibility gene 2 protein-like.
    
 0.940
ENSSGRP00000014979
Autism susceptibility gene 2 protein-like isoform X1.
    
 0.934
LOC107582750
Autism susceptibility gene 2 protein-like isoform X1.
    
 0.934
Your Current Organism:
Sinocyclocheilus grahami
NCBI taxonomy Id: 75366
Other names: S. grahami
Server load: low (24%) [HD]