STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC107585723Gamma-secretase subunit PEN-2-like. (101 aa)    
Predicted Functional Partners:
ENSSGRP00000110423
Nicastrin-like.
    
 0.997
psen2
Presenilin-2 isoform X1.
    
 0.994
ENSSGRP00000086220
Presenilin-1-like.
    
 0.994
ENSSGRP00000010421
Gamma-secretase subunit Aph-1b-like.
   
 0.993
ENSSGRP00000041314
Gamma-secretase subunit Aph-1b-like.
   
 0.993
LOC107572192
Gamma-secretase subunit Aph-1b-like.
   
 0.991
ENSSGRP00000088023
annotation not available
    
 0.990
ENSSGRP00000040426
Presenilin 1.
    
 0.974
ENSSGRP00000025706
Presenilin 2.
    
 0.973
ENSSGRP00000055938
annotation not available
   
 0.966
Your Current Organism:
Sinocyclocheilus grahami
NCBI taxonomy Id: 75366
Other names: S. grahami
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.