Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSSGRP00000001859ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae). (404 aa)    
Predicted Functional Partners:
utp18
U3 small nucleolar RNA-associated protein 18 homolog.
   
 
 0.971
ENSSGRP00000041844
Protein AATF-like isoform X1.
   
 
 0.970
ENSSGRP00000013069
UTP3 small subunit processome component.
   
 
 0.966
ddx10
Probable ATP-dependent RNA helicase DDX10.
   
 
 0.965
ENSSGRP00000103804
Probable ATP-dependent RNA helicase DDX10.
   
 
 0.965
ENSSGRP00000084572
Ribosome biogenesis protein ENP2.
   
 
 0.963
ENSSGRP00000085722
Ribosome biogenesis protein ENP2.
   
 
 0.963
ENSSGRP00000031624
UTP6 small subunit processome component.
   
 
 0.954
utp6
U3 small nucleolar RNA-associated protein 6 homolog isoform X1.
   
 
 0.954
Pdcd11
RRNA biogenesis protein RRP5.
   
 
 0.953
Your Current Organism:
Sinocyclocheilus grahami
NCBI taxonomy Id: 75366
Other names: S. grahami
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.