STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC107591759E3 ubiquitin-protein ligase SMURF1 isoform X1. (768 aa)    
Predicted Functional Partners:
LOC107599897
Protein patched homolog 1.
    
 0.967
LOC107557169
Protein patched homolog 1-like.
    
 0.967
Ptch1
Protein patched homolog 1.
    
 0.967
Smad7
Mothers against decapentaplegic homolog 7.
    
 0.960
LOC107585655
Mothers against decapentaplegic homolog 7-like.
    
 0.960
smad6
Mothers against decapentaplegic homolog 6.
    
 0.959
ENSSGRP00000070226
Mothers against decapentaplegic homolog 6-like isoform X1.
    
 0.959
LOC107583766
Mothers against decapentaplegic homolog 6-like.
    
 0.943
LOC107596967
Mothers against decapentaplegic homolog 6-like.
    
 0.943
ENSSGRP00000046802
TGF-beta receptor type-1-like.
    
 0.863
Your Current Organism:
Sinocyclocheilus grahami
NCBI taxonomy Id: 75366
Other names: S. grahami
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.