Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSSGRP00000004331NCK adaptor protein 2b. (153 aa)    
Predicted Functional Partners:
Lcp2
Lymphocyte cytosolic protein 2.
    
 0.951
LOC107566210
Serine/threonine-protein kinase PAK 3 isoform X1.
    
 0.921
ENSSGRP00000066097
P21 protein (Cdc42/Rac)-activated kinase 1.
    
 0.914
pak1
Serine/threonine-protein kinase PAK 1 isoform X1.
    
 0.914
Pak2
Serine/threonine-protein kinase PAK 2.
    
 0.888
LOC107591323
Serine/threonine-protein kinase PAK 2-like.
    
 0.888
ENSSGRP00000064700
Serine/threonine-protein kinase PAK 2-like.
    
 0.888
LOC107557297
Serine/threonine-protein kinase PAK 2-like.
    
 0.888
pak5
Serine/threonine-protein kinase PAK 7 isoform X1.
    
 0.859
LOC107585589
Serine/threonine-protein kinase PAK 4-like isoform X1.
    
 0.859
Your Current Organism:
Sinocyclocheilus grahami
NCBI taxonomy Id: 75366
Other names: S. grahami
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