Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSSGRP00000005083Histone H2B. (151 aa)    
Predicted Functional Partners:
ENSSGRP00000082318
Core histone macro-H2A.1.
  
 0.865
ENSSGRP00000012765
Core histone macro-H2A.2-like.
   
 0.848
LOC107589552
Core histone macro-H2A.2.
   
 0.848
ENSSGRP00000083272
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
 0.846
ENSSGRP00000106616
annotation not available
    
 0.846
ENSSGRP00000027242
Histone H2AX.
  
 0.841
ENSSGRP00000016017
H2A.X variant histone.
  
 0.837
ENSSGRP00000016018
H2A.X variant histone.
  
 0.837
LOC107555719
Histone H4-like.
  
 0.810
LOC107555719-2
Histone H4.
  
 0.810
Your Current Organism:
Sinocyclocheilus grahami
NCBI taxonomy Id: 75366
Other names: S. grahami
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