Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC107594447Probable E3 ubiquitin-protein ligase HERC3. (922 aa)    
Predicted Functional Partners:
ENSSGRP00000098917
Probable E3 ubiquitin-protein ligase HERC1.
   
 0.745
LOC107599945
Cellular tumor antigen p53.
    
 0.700
LOC107592291
Cellular tumor antigen p53-like.
    
 0.700
LOC107548991
Ubiquitin-conjugating enzyme E2 L3-like.
   
 0.694
LOC107599129
Ubiquitin-conjugating enzyme E2 L3.
   
 0.694
LOC107602229
Ubiquitin-conjugating enzyme E2 L3-like.
   
 0.694
Trip12
E3 ubiquitin-protein ligase TRIP12.
   
 
 0.692
ENSSGRP00000084766
E3 ubiquitin-protein ligase TRIP12-like.
   
 
 0.692
ENSSGRP00000049971
annotation not available
    
 0.613
TSC2
TSC complex subunit 2.
    
 0.613
Your Current Organism:
Sinocyclocheilus grahami
NCBI taxonomy Id: 75366
Other names: S. grahami
Server load: low (10%) [HD]