Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSSGRP00000010396SMAD family member 4b. (464 aa)    
Predicted Functional Partners:
smad2
Mothers against decapentaplegic homolog 2.
   
0.953
SMAD9
Mothers against decapentaplegic homolog 9-like isoform X1.
   
0.953
SMAD9-2
SMAD family member 9.
   
0.953
LOC107599811
Ski oncogene-like.
    
 0.951
LOC107548407
Ski oncogene-like.
    
 0.951
smad3
Mothers against decapentaplegic homolog 3.
   
0.949
ENSSGRP00000013976
SMAD family member 1.
   
0.949
ENSSGRP00000062617
Mothers against decapentaplegic homolog 1.
   
0.949
LOC107553101
Mothers against decapentaplegic homolog 3.
   
0.949
ENSSGRP00000036217
annotation not available
   
0.945
Your Current Organism:
Sinocyclocheilus grahami
NCBI taxonomy Id: 75366
Other names: S. grahami
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