Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC107562955Replication protein A 70 kDa DNA-binding subunit isoform X1. (603 aa)    
Predicted Functional Partners:
top3a
DNA topoisomerase 3-alpha.
   
 0.995
ENSSGRP00000089578
BLM RecQ like helicase.
   
 0.993
Rpa2
Replication protein A 32 kDa subunit isoform X1.
   
 0.992
ENSSGRP00000064987
BLM RecQ like helicase.
   
 0.988
ENSSGRP00000009235
annotation not available
   
 0.987
LOC107598208
Replication protein A 14 kDa subunit-like.
   
 0.987
LOC107568286
Replication protein A 14 kDa subunit-like.
   
 0.987
ENSSGRP00000017699
Proliferating cell nuclear antigen.
   
 0.984
LOC107583397
Proliferating cell nuclear antigen.
   
 0.984
ENSSGRP00000070027
RecQ-mediated genome instability protein 1-like.
    
 0.980
Your Current Organism:
Sinocyclocheilus grahami
NCBI taxonomy Id: 75366
Other names: S. grahami
Server load: low (34%) [HD]