Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSSGRP00000010868Caspase-8-like. (240 aa)    
Predicted Functional Partners:
LOC107559437
FAS-associated death domain protein-like.
   
 0.984
ENSSGRP00000029960
Receptor-interacting serine-threonine kinase 3.
   
 0.950
ENSSGRP00000059563
Receptor-interacting serine-threonine kinase 3.
   
 0.950
Ripk1
Receptor-interacting serine/threonine-protein kinase 1.
   
 0.947
LOC107585960
Tumor necrosis factor receptor type 1-associated DEATH domain protein.
   
 0.945
LOC107594616
Tumor necrosis factor receptor type 1-associated DEATH domain protein-like.
   
 0.945
ENSSGRP00000011951
PYD and CARD domain containing.
   
 0.940
ENSSGRP00000034418
PYD and CARD domain containing.
   
 0.940
ENSSGRP00000018945
annotation not available
   
 0.921
ENSSGRP00000051562
Receptor (TNFRSF)-interacting serine-threonine kinase 1, like.
   
 0.921
Your Current Organism:
Sinocyclocheilus grahami
NCBI taxonomy Id: 75366
Other names: S. grahami
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