Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ENSSGRP00000011353Piezo-type mechanosensitive ion channel component 1. (1930 aa)    
Predicted Functional Partners:
ENSSGRP00000038462
Checkpoint kinase 2.
    
 0.869
ENSSGRP00000079966
Checkpoint kinase 2.
    
 0.869
tipin
TIMELESS interacting protein.
   
 
 0.861
ENSSGRP00000079905
Timeless circadian clock.
   
 
 0.854
ENSSGRP00000060599
WD repeat and HMG-box DNA-binding protein 1-like.
   
 
 0.837
ENSSGRP00000072302
WD repeat and HMG-box DNA-binding protein 1-like isoform X1.
   
 
 0.837
Cdc45
Cell division control protein 45 homolog.
   
 0.818
ENSSGRP00000057412
CDC45 cell division cycle 45 homolog (S. cerevisiae).
   
 0.818
ENSSGRP00000005630
Serine/threonine-protein kinase ATR-like.
   
 0.817
ENSSGRP00000024514
ATR serine/threonine kinase.
   
 0.817
Your Current Organism:
Sinocyclocheilus grahami
NCBI taxonomy Id: 75366
Other names: S. grahami
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