Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pkp4Plakophilin-4 isoform X1. (1132 aa)    
Predicted Functional Partners:
ctnnb1
Catenin beta 1.
   
 0.779
LOC107570993
Catenin beta-1 isoform X1.
   
 0.779
ENSSGRP00000067405
Catenin beta-1-like.
   
 0.779
LOC107592060
Catenin beta-1-like.
   
 0.779
LOC107573466
Catenin alpha-2-like.
   
 0.751
ctnna2
Catenin alpha-2.
   
 0.751
ENSSGRP00000019399
annotation not available
   
 0.751
ENSSGRP00000077935
Catenin (cadherin-associated protein), alpha 2.
   
 0.751
ENSSGRP00000077979
Catenin alpha-2-like.
   
 0.751
ENSSGRP00000097096
annotation not available
   
 0.751
Your Current Organism:
Sinocyclocheilus grahami
NCBI taxonomy Id: 75366
Other names: S. grahami
Server load: medium (56%) [HD]