Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSSGRP00000011830Tryptophan 2,3-dioxygenase a. (418 aa)    
Predicted Functional Partners:
ENSSGRP00000002868
annotation not available
  
 
 0.959
ENSSGRP00000009500
annotation not available
  
 
 0.959
ENSSGRP00000087031
Kynureninase-like.
  
 
 0.959
ENSSGRP00000015390
annotation not available
   
 
 0.952
ENSSGRP00000096962
Indoleamine 2,3-dioxygenase 2-like isoform X1.
   
 
 0.952
ENSSGRP00000005041
annotation not available
  
 
 0.937
Afmid
Kynurenine formamidase isoform X1.
  
 
 0.937
LOC107564603
Tryptophan 5-hydroxylase 1-like isoform X1.
  
 
 0.881
ENSSGRP00000051766
Tryptophan 5-hydroxylase-like isoform X1.
  
 
 0.881
ENSSGRP00000062919
Tryptophan 5-hydroxylase 2-like.
  
 
 0.881
Your Current Organism:
Sinocyclocheilus grahami
NCBI taxonomy Id: 75366
Other names: S. grahami
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.