Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSSGRP00000012138SH2 domain containing 3Ca. (603 aa)    
Predicted Functional Partners:
ENSSGRP00000008715
Enhancer of filamentation 1-like.
    
 0.578
LOC107583722
Breast cancer anti-estrogen resistance protein 1-like isoform X1.
    
 0.578
nedd9
Enhancer of filamentation 1.
    
 0.578
LOC107596915
Breast cancer anti-estrogen resistance protein 1-like isoform X1.
    
 0.578
LOC107556357
Cas scaffolding protein family member 4-like.
    
 0.547
ENSSGRP00000109791
Cas scaffold protein family member 4.
    
 0.547
ENSSGRP00000014469
Potassium voltage-gated channel, Isk-related family, member 4.
     
 0.537
LOC107558850
Potassium voltage-gated channel Isk-related subfamily E member 4.
     
 0.537
LOC107562533
Breast cancer anti-estrogen resistance protein 1-like isoform X1.
    
 0.528
ENSSGRP00000011528
WD repeat domain 90.
    
  0.462
Your Current Organism:
Sinocyclocheilus grahami
NCBI taxonomy Id: 75366
Other names: S. grahami
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