STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC107586821Serine/threonine-protein kinase PLK4 isoform X1. (940 aa)    
Predicted Functional Partners:
stil
SCL-interrupting locus protein isoform X1.
   
 
 0.992
ENSSGRP00000047575
Extra spindle pole bodies like 1, separase.
   
 0.973
Bub1
Mitotic checkpoint serine/threonine-protein kinase BUB1.
   
 0.972
ENSSGRP00000063930
Centrosomal protein 192.
    
 0.972
CEP192
Centrosomal protein 192.
    
 0.972
ENSSGRP00000012934
Intersectin 2a.
    
 0.930
ENSSGRP00000074134
Intersectin-2-like.
    
 0.930
ENSSGRP00000084141
Intersectin 2b.
    
 0.930
LOC107594821
Intersectin-2-like isoform X1.
    
 0.930
ENSSGRP00000024846
annotation not available
   
 0.910
Your Current Organism:
Sinocyclocheilus grahami
NCBI taxonomy Id: 75366
Other names: S. grahami
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.