Tint_0002 protein (Thiomonas intermedia) - STRING interaction network

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Tint_0002

DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (371 aa)

Predicted Functional Partners:

Tint_0146

0.998

Tint_1479

0.998

dnaX

0.998

dnaQ

0.996

Tint_2438

0.994

Tint_1029

0.993

Tint_2578

0.990

polA

0.975

Tint_1063

0.945

mutL

0.933

Your Current Organism:

Thiomonas intermedia

NCBI taxonomy Id: 75379
Other names: T. intermedia K12, Thiobacillus intermedius K12, Thiomonas intermedia K12, Thiomonas intermedia str. K12, Thiomonas intermedia strain K12

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Tint_0002	Tint_0146	Tint_0002	Tint_0146	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	TIGRFAM: DNA polymerase III, delta subunit; KEGG: bac:BamMC406_0577 DNA polymerase III subunit delta; PFAM: DNA polymerase III delta.	0.998
Tint_0002	Tint_1029	Tint_0002	Tint_1029	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	Sigma 54 interacting domain protein; KEGG: bmj:BMULJ_00613 DnaA regulatory inactivator Hda; PFAM: Chromosomal replication initiator DnaA; SMART: AAA ATPase; Belongs to the DnaA family.	0.993
Tint_0002	Tint_1063	Tint_0002	Tint_1063	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA polymerase III, epsilon subunit; SMART: Exonuclease; Excinuclease ABC C subunit domain protein; TIGRFAM: DNA polymerase III, epsilon subunit; KEGG: rfr:Rfer_2572 DNA polymerase III, epsilon subunit; PFAM: Exonuclease RNase T and DNA polymerase III; Excinuclease ABC C subunit domain protein.	0.945
Tint_0002	Tint_1479	Tint_0002	Tint_1479	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	KEGG: bpt:Bpet2503 DNA polymerase III, delta' subunit.	0.998
Tint_0002	Tint_2438	Tint_0002	Tint_2438	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA polymerase III, alpha subunit; SMART: phosphoesterase PHP domain protein; TIGRFAM: DNA polymerase III, alpha subunit; KEGG: bte:BTH_I0984 DNA polymerase III subunit alpha; PFAM: DNA polymerase III alpha subunit; PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type.	0.994
Tint_0002	Tint_2578	Tint_0002	Tint_2578	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	PFAM: DNA polymerase III chi subunit HolC; KEGG: bpt:Bpet1770 DNA polymerase III, chi subunit.	0.990
Tint_0002	dnaQ	Tint_0002	Tint_1362	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	0.996
Tint_0002	dnaX	Tint_0002	Tint_1856	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.	0.998
Tint_0002	mutL	Tint_0002	Tint_1241	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.	0.933
Tint_0002	polA	Tint_0002	Tint_1248	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.975
Tint_0146	Tint_0002	Tint_0146	Tint_0002	TIGRFAM: DNA polymerase III, delta subunit; KEGG: bac:BamMC406_0577 DNA polymerase III subunit delta; PFAM: DNA polymerase III delta.	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.998
Tint_0146	Tint_1029	Tint_0146	Tint_1029	TIGRFAM: DNA polymerase III, delta subunit; KEGG: bac:BamMC406_0577 DNA polymerase III subunit delta; PFAM: DNA polymerase III delta.	Sigma 54 interacting domain protein; KEGG: bmj:BMULJ_00613 DnaA regulatory inactivator Hda; PFAM: Chromosomal replication initiator DnaA; SMART: AAA ATPase; Belongs to the DnaA family.	0.468
Tint_0146	Tint_1063	Tint_0146	Tint_1063	TIGRFAM: DNA polymerase III, delta subunit; KEGG: bac:BamMC406_0577 DNA polymerase III subunit delta; PFAM: DNA polymerase III delta.	DNA polymerase III, epsilon subunit; SMART: Exonuclease; Excinuclease ABC C subunit domain protein; TIGRFAM: DNA polymerase III, epsilon subunit; KEGG: rfr:Rfer_2572 DNA polymerase III, epsilon subunit; PFAM: Exonuclease RNase T and DNA polymerase III; Excinuclease ABC C subunit domain protein.	0.953
Tint_0146	Tint_1479	Tint_0146	Tint_1479	TIGRFAM: DNA polymerase III, delta subunit; KEGG: bac:BamMC406_0577 DNA polymerase III subunit delta; PFAM: DNA polymerase III delta.	KEGG: bpt:Bpet2503 DNA polymerase III, delta' subunit.	0.998
Tint_0146	Tint_2438	Tint_0146	Tint_2438	TIGRFAM: DNA polymerase III, delta subunit; KEGG: bac:BamMC406_0577 DNA polymerase III subunit delta; PFAM: DNA polymerase III delta.	DNA polymerase III, alpha subunit; SMART: phosphoesterase PHP domain protein; TIGRFAM: DNA polymerase III, alpha subunit; KEGG: bte:BTH_I0984 DNA polymerase III subunit alpha; PFAM: DNA polymerase III alpha subunit; PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type.	0.992
Tint_0146	Tint_2578	Tint_0146	Tint_2578	TIGRFAM: DNA polymerase III, delta subunit; KEGG: bac:BamMC406_0577 DNA polymerase III subunit delta; PFAM: DNA polymerase III delta.	PFAM: DNA polymerase III chi subunit HolC; KEGG: bpt:Bpet1770 DNA polymerase III, chi subunit.	0.995
Tint_0146	dnaQ	Tint_0146	Tint_1362	TIGRFAM: DNA polymerase III, delta subunit; KEGG: bac:BamMC406_0577 DNA polymerase III subunit delta; PFAM: DNA polymerase III delta.	DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	0.988
Tint_0146	dnaX	Tint_0146	Tint_1856	TIGRFAM: DNA polymerase III, delta subunit; KEGG: bac:BamMC406_0577 DNA polymerase III subunit delta; PFAM: DNA polymerase III delta.	DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.	0.997
Tint_0146	mutL	Tint_0146	Tint_1241	TIGRFAM: DNA polymerase III, delta subunit; KEGG: bac:BamMC406_0577 DNA polymerase III subunit delta; PFAM: DNA polymerase III delta.	DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.	0.450
Tint_0146	polA	Tint_0146	Tint_1248	TIGRFAM: DNA polymerase III, delta subunit; KEGG: bac:BamMC406_0577 DNA polymerase III subunit delta; PFAM: DNA polymerase III delta.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.641

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