Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tint_0484PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; KEGG: vei:Veis_2069 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. (328 aa)    
Predicted Functional Partners:
Tint_2855
KEGG: ajs:Ajs_1122 hydroxypyruvate reductase; PFAM: MOFRL domain protein.
 
 0.957
Tint_2718
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: bgl:bglu_1g32580 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding.
 
  
0.926
Tint_2796
TIGRFAM: malate synthase A; KEGG: rpf:Rpic12D_1302 malate synthase A; PFAM: Malate synthase family protein; Belongs to the malate synthase family.
   
 
 0.916
Tint_0605
PFAM: FAD linked oxidase domain protein; KEGG: azo:azo1000 glycolate oxidase FAD binding subunit.
   
 0.913
Tint_0606
PFAM: FAD linked oxidase domain protein; KEGG: vap:Vapar_0222 FAD linked oxidase domain protein.
   
 0.913
Tint_0027
TIGRFAM: lactoylglutathione lyase; KEGG: pol:Bpro_3549 glyoxalase I; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase.
   
 0.911
Tint_1382
KEGG: bph:Bphy_1368 isocitrate lyase; TIGRFAM: isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase.
     
 0.911
Tint_2353
KEGG: rso:RSc2429 oxidoreductase protein; PFAM: 6-phosphogluconate dehydrogenase NAD-binding.
    
 0.910
Tint_2856
TIGRFAM: 2-hydroxy-3-oxopropionate reductase; KEGG: har:HEAR0334 tartronic semialdehyde reductase; PFAM: 6-phosphogluconate dehydrogenase NAD-binding.
    
 0.910
Tint_0009
TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; KEGG: cvi:CV_0143 2-dehydro-3-deoxy-phosphogluconate aldolase; PFAM: KDPG and KHG aldolase.
    
  0.906
Your Current Organism:
Thiomonas intermedia
NCBI taxonomy Id: 75379
Other names: T. intermedia K12, Thiobacillus intermedius K12, Thiomonas intermedia K12, Thiomonas intermedia str. K12, Thiomonas intermedia strain K12
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