STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tint_1228Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; GGDEF domain containing protein; PAS fold-3 domain protein; PAS fold-4 domain protein; KEGG: cja:CJA_1985 sensory box/GGDEF family protein; SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein. (1082 aa)    
Predicted Functional Partners:
Tint_2517
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; GGDEF domain containing protein; PAS fold-4 domain protein; KEGG: rfr:Rfer_2893 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); SMART: GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein; EAL domain protein.
 
 
0.903
Tint_0305
Diguanylate phosphodiesterase; KEGG: aca:ACP_0922 bacterial signalling protein N terminal repeat/GGDEF/EAL domain protein; PFAM: EAL domain protein; SMART: EAL domain protein.
 
 
0.860
Tint_1227
MCP methyltransferase, CheR-type; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
 
  
 0.798
cheD
CheD; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.
       0.777
Tint_1256
TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; CBS domain containing protein; GGDEF domain containing protein; KEGG: har:HEAR1023 hypothetical protein; SMART: EAL domain protein; GGDEF domain containing protein.
 
 
0.775
Tint_1229
KEGG: app:CAP2UW1_3447 methyl-accepting chemotaxis sensory transducer; PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein.
  
 
 0.751
Tint_1179
Diguanylate phosphodiesterase with GAF sensor(s); KEGG: bxe:Bxe_B2627 GAF sensor diguanylate phosphsdiesterase; PFAM: EAL domain protein; GAF domain protein; SMART: EAL domain protein.
 
 
0.749
Tint_0914
Diguanylate cyclase with GAF sensor; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein; KEGG: hna:Hneap_0485 diguanylate cyclase with PAS/PAC and GAF sensors; SMART: GGDEF domain containing protein; GAF domain protein.
 
 
0.737
Tint_3172
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: cvi:CV_0387 hypothetical protein; SMART: GGDEF domain containing protein.
 
0.737
Tint_2642
KEGG: dar:Daro_2752 metal-dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region.
 
 
 
 0.731
Your Current Organism:
Thiomonas intermedia
NCBI taxonomy Id: 75379
Other names: T. intermedia K12, Thiobacillus intermedius K12, Thiomonas intermedia K12, Thiomonas intermedia str. K12, Thiomonas intermedia strain K12
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.