node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Tint_2125 | lpxB | Tint_2125 | Tint_2127 | PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: lch:Lcho_2835 tRNA/rRNA methyltransferase (SpoU). | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.849 |
Tint_2125 | mnmE | Tint_2125 | Tint_3194 | PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: lch:Lcho_2835 tRNA/rRNA methyltransferase (SpoU). | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.834 |
Tint_2125 | rnhB | Tint_2125 | Tint_2126 | PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: lch:Lcho_2835 tRNA/rRNA methyltransferase (SpoU). | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.852 |
Tint_2125 | rplC | Tint_2125 | Tint_2878 | PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: lch:Lcho_2835 tRNA/rRNA methyltransferase (SpoU). | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.815 |
Tint_2125 | rplK | Tint_2125 | Tint_3110 | PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: lch:Lcho_2835 tRNA/rRNA methyltransferase (SpoU). | Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.810 |
Tint_2125 | rplM | Tint_2125 | Tint_0237 | PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: lch:Lcho_2835 tRNA/rRNA methyltransferase (SpoU). | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.862 |
Tint_2125 | rplO | Tint_2125 | Tint_2617 | PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: lch:Lcho_2835 tRNA/rRNA methyltransferase (SpoU). | Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.810 |
Tint_2125 | rplQ | Tint_2125 | Tint_2609 | PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: lch:Lcho_2835 tRNA/rRNA methyltransferase (SpoU). | KEGG: bpy:Bphyt_3617 50S ribosomal protein L17; TIGRFAM: ribosomal protein L17; PFAM: ribosomal protein L17. | 0.812 |
Tint_2125 | rplU | Tint_2125 | Tint_0511 | PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: lch:Lcho_2835 tRNA/rRNA methyltransferase (SpoU). | Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.811 |
Tint_2125 | rsfS | Tint_2125 | Tint_2357 | PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: lch:Lcho_2835 tRNA/rRNA methyltransferase (SpoU). | Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.864 |
lpxB | Tint_2125 | Tint_2127 | Tint_2125 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: lch:Lcho_2835 tRNA/rRNA methyltransferase (SpoU). | 0.849 |
lpxB | rnhB | Tint_2127 | Tint_2126 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.950 |
mnmE | Tint_2125 | Tint_3194 | Tint_2125 | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: lch:Lcho_2835 tRNA/rRNA methyltransferase (SpoU). | 0.834 |
mnmE | rplC | Tint_3194 | Tint_2878 | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.808 |
mnmE | rplK | Tint_3194 | Tint_3110 | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.835 |
mnmE | rplM | Tint_3194 | Tint_0237 | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.859 |
mnmE | rplO | Tint_3194 | Tint_2617 | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.870 |
mnmE | rplQ | Tint_3194 | Tint_2609 | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | KEGG: bpy:Bphyt_3617 50S ribosomal protein L17; TIGRFAM: ribosomal protein L17; PFAM: ribosomal protein L17. | 0.845 |
mnmE | rplU | Tint_3194 | Tint_0511 | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.856 |
mnmE | rsfS | Tint_3194 | Tint_2357 | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.822 |