STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tint_2425TIGRFAM: riboflavin synthase, alpha subunit; KEGG: rfr:Rfer_2667 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein. (210 aa)    
Predicted Functional Partners:
Tint_2424
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
 0.999
ribB
Hypothetical protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
 
 0.999
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
 
 0.998
Tint_1329
Riboflavin biosynthesis protein RibF; KEGG: lch:Lcho_1237 bifunctional riboflavin kinase/FMN adenylyltransferase; TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; Belongs to the ribF family.
  
 
 0.941
hisI
phosphoribosyl-ATP diphosphatase; KEGG: abb:ABBFA_003189 histidine biosynthesis bifunctional protein hisIE; TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; In the N-terminal section; belongs to the PRA-CH family.
  
    0.798
Tint_2426
PFAM: glutamine amidotransferase class-II; KEGG: mgm:Mmc1_0879 glutamine amidotransferase, class-II.
       0.776
Tint_1743
KEGG: mpt:Mpe_A1281 50S ribosomal protein L31P; TIGRFAM: ribosomal protein L31; PFAM: ribosomal protein L31; Belongs to the bacterial ribosomal protein bL31 family.
   
    0.691
Tint_2899
PFAM: Flavocytochrome c sulphide dehydrogenase flavin-binding; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: mpt:Mpe_A2429 sulfide dehydrogenase (flavocytochrome), flavoprotein subunit.
   
    0.691
nrdR
ATP-cone domain protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
     
 0.586
Tint_2964
PFAM: General substrate transporter; KEGG: mpt:Mpe_A3350 putative sugar transport protein.
   
    0.532
Your Current Organism:
Thiomonas intermedia
NCBI taxonomy Id: 75379
Other names: T. intermedia K12, Thiobacillus intermedius K12, Thiomonas intermedia K12, Thiomonas intermedia str. K12, Thiomonas intermedia strain K12
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