Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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Tint_2467Cysteine desulfurase, SufS subfamily; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. (416 aa)    
Predicted Functional Partners:
Tint_2466
KEGG: gvi:glr1374 hypothetical protein; TIGRFAM: SUF system FeS assembly protein, NifU family; PFAM: nitrogen-fixing NifU domain protein.
 
 0.995
Tint_2469
TIGRFAM: FeS assembly ATPase SufC; PFAM: ABC transporter related; KEGG: tmz:Tmz1t_1898 FeS assembly ATPase SufC; SMART: AAA ATPase.
 
  
 0.991
Tint_2468
KEGG: ank:AnaeK_0891 FeS assembly protein SufD; TIGRFAM: FeS assembly protein SufD; PFAM: SufBD protein.
 
 
 0.988
Tint_2470
KEGG: tmz:Tmz1t_1899 FeS assembly protein SufB; TIGRFAM: FeS assembly protein SufB; PFAM: SufBD protein.
 
 
 0.985
Tint_1058
FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
  
 0.968
Tint_2465
KEGG: hha:Hhal_1972 hypothetical protein; TIGRFAM: FeS assembly SUF system protein SufT; PFAM: protein of unknown function DUF59.
 
  
 0.939
Tint_2417
TIGRFAM: thioredoxin reductase; KEGG: mmb:Mmol_1437 thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
 
 
  0.918
selD
Selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP.
   
 0.909
Tint_1040
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: mpt:Mpe_A1496 thioredoxin reductase.
  
 
  0.904
iscS
Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
  
 
0.853
Your Current Organism:
Thiomonas intermedia
NCBI taxonomy Id: 75379
Other names: T. intermedia K12, Thiobacillus intermedius K12, Thiomonas intermedia K12, Thiomonas intermedia str. K12, Thiomonas intermedia strain K12
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