| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CBL55502.1 | CBL55503.1 | PFREUD_00020 | PFREUD_00030 | Multidrug resistance transporter, MFS superfamily protein; Belongs to the major facilitator superfamily. | Transcriptional regulator. | 0.461 |
| CBL55503.1 | CBL55502.1 | PFREUD_00030 | PFREUD_00020 | Transcriptional regulator. | Multidrug resistance transporter, MFS superfamily protein; Belongs to the major facilitator superfamily. | 0.461 |
| CBL55503.1 | CBL57095.1 | PFREUD_00030 | PFREUD_15970 | Transcriptional regulator. | Glutamine synthetase; Glutamate metabolism : ATP + L-Glutamate + NH3 <=> ADP + Orthophosphate + L-Glutamine, Peptidoglycan biosynthesis. | 0.404 |
| CBL55503.1 | dnaJ1 | PFREUD_00030 | PFREUD_17820 | Transcriptional regulator. | Chaperone protein dnaJ 1 (DnaJ1 protein) (Heat shock protein 40 1); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds o [...] | 0.468 |
| CBL55503.1 | dnaJ2 | PFREUD_00030 | PFREUD_04650 | Transcriptional regulator. | Chaperone protein dnaJ 2 (DnaJ2 protein) (Heat shock protein 40 2); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds o [...] | 0.468 |
| CBL55503.1 | dnaJ3 | PFREUD_00030 | PFREUD_08760 | Transcriptional regulator. | Chaperone protein dnaJ 3 (DnaJ3 protein) (Heat shock protein 40 3); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds o [...] | 0.468 |
| CBL55503.1 | glnA | PFREUD_00030 | PFREUD_16030 | Transcriptional regulator. | Glutamine synthetase; # ATP + L-Glutamate + NH3 <=> ADP + Orthophosphate + L-Glutamine; Belongs to the glutamine synthetase family. | 0.404 |
| CBL55503.1 | rpoB | PFREUD_00030 | PFREUD_05600 | Transcriptional regulator. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.414 |
| CBL57095.1 | CBL55503.1 | PFREUD_15970 | PFREUD_00030 | Glutamine synthetase; Glutamate metabolism : ATP + L-Glutamate + NH3 <=> ADP + Orthophosphate + L-Glutamine, Peptidoglycan biosynthesis. | Transcriptional regulator. | 0.404 |
| CBL57095.1 | glnA | PFREUD_15970 | PFREUD_16030 | Glutamine synthetase; Glutamate metabolism : ATP + L-Glutamate + NH3 <=> ADP + Orthophosphate + L-Glutamine, Peptidoglycan biosynthesis. | Glutamine synthetase; # ATP + L-Glutamate + NH3 <=> ADP + Orthophosphate + L-Glutamine; Belongs to the glutamine synthetase family. | 0.919 |
| CBL57095.1 | rpoB | PFREUD_15970 | PFREUD_05600 | Glutamine synthetase; Glutamate metabolism : ATP + L-Glutamate + NH3 <=> ADP + Orthophosphate + L-Glutamine, Peptidoglycan biosynthesis. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.461 |
| dnaJ1 | CBL55503.1 | PFREUD_17820 | PFREUD_00030 | Chaperone protein dnaJ 1 (DnaJ1 protein) (Heat shock protein 40 1); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds o [...] | Transcriptional regulator. | 0.468 |
| dnaJ2 | CBL55503.1 | PFREUD_04650 | PFREUD_00030 | Chaperone protein dnaJ 2 (DnaJ2 protein) (Heat shock protein 40 2); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds o [...] | Transcriptional regulator. | 0.468 |
| dnaJ3 | CBL55503.1 | PFREUD_08760 | PFREUD_00030 | Chaperone protein dnaJ 3 (DnaJ3 protein) (Heat shock protein 40 3); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds o [...] | Transcriptional regulator. | 0.468 |
| glnA | CBL55503.1 | PFREUD_16030 | PFREUD_00030 | Glutamine synthetase; # ATP + L-Glutamate + NH3 <=> ADP + Orthophosphate + L-Glutamine; Belongs to the glutamine synthetase family. | Transcriptional regulator. | 0.404 |
| glnA | CBL57095.1 | PFREUD_16030 | PFREUD_15970 | Glutamine synthetase; # ATP + L-Glutamate + NH3 <=> ADP + Orthophosphate + L-Glutamine; Belongs to the glutamine synthetase family. | Glutamine synthetase; Glutamate metabolism : ATP + L-Glutamate + NH3 <=> ADP + Orthophosphate + L-Glutamine, Peptidoglycan biosynthesis. | 0.919 |
| rpoB | CBL55503.1 | PFREUD_05600 | PFREUD_00030 | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Transcriptional regulator. | 0.414 |
| rpoB | CBL57095.1 | PFREUD_05600 | PFREUD_15970 | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Glutamine synthetase; Glutamate metabolism : ATP + L-Glutamate + NH3 <=> ADP + Orthophosphate + L-Glutamine, Peptidoglycan biosynthesis. | 0.461 |